Butamoxane

Butamoxane

SCHEMBL2111074

CCCCNCC1COc2ccccc2O1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.81
ESR2 Q92731 1/20 0.81
SMN1; SMN2 Q16637 1/20 0.71
ALDH1A1 P00352 6/20 0.69
ADRA1D P25100 6/20 0.60
ADRA1A P35348 6/20 0.60
ADRA1B P35368 6/20 0.60
HTR1A P08908 4/20 0.57
MEN1 O00255 2/20 0.57
CYP3A4 P08684 2/20 0.57
KMT2A Q03164 2/20 0.57
KDM4E B2RXH2 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
TSHR P16473 1/20 0.57
MAPK1 P28482 1/20 0.57
CYP2C19 P33261 1/20 0.57
THPO P40225 1/20 0.57
ALOX5 P09917 1/20 0.57
ADRA2A P08913 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butamoxane SCHEMBL29354372 1.00 POLB (0.81) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL29353196 0.91 POLB (0.97) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL10864903 0.91 POLB (0.97) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL7460800 0.85 SMN1; SMN2 (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL7277047 0.85 SMN1; SMN2 (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL8797418 0.85 SMN1; SMN2 (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL7463106 0.85 SMN1; SMN2 (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL7460809 0.85 SMN1; SMN2 (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL9619567 0.85 POLB (0.71) POLBESR2SMN1; SMN2ALDH1A1ADRA1D
SCHEMBL18358970 0.84 POLB (0.75) POLBESR2SMN1; SMN2ALDH1A1ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-12102653-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2024-10-01 US disclosed
US-20240000841-A1 LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM ST ANNA KINDERKREBSFORSCHUNG (AT) 2024-01-04 US disclosed
US-11844813-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2023-12-19 US disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 US disclosed
US-20210386781-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) UNIVERSITÄT FÜR BODENKULTUR WIEN (AT) 2021-12-16 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-20050002865-A1 Diagnostic/therapeutic agents AMERSHAM HEALTH AS (NO) 2005-01-06 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 POLB 989/4885ESR2 1745/4885SMN1; SMN2 1551/4885
US-20050002865-A1 Diagnostic/therapeutic agents FUS, HNRNPF, HNRNPR POLB 648/4885ESR2 1111/4885SMN1; SMN2 1857/4885
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 POLB 4881/4885ESR2 1225/4885SMN1; SMN2 4302/4885
US-20210386781-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CD74, HAVCR2, CD2BP2 POLB 4811/4885ESR2 1723/4885SMN1; SMN2 4079/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 POLB 967/4885ESR2 1929/4885SMN1; SMN2 1978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.