Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL376380 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL21110973 | 0.87 | ALDH1A1 (0.46) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL20479732 | 0.82 | TSHR (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL143841 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL15415329 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL146869 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL6758979 | 0.79 | ALDH1A1 (0.62) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL21946019 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL21945750 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL21945751 | 0.77 | ALDH1A1 (0.60) | ALDH1A1GAACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508482-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR AND USE THEREOF | Nanjing Transthera Biosciences Co. Ltd. (CN) | 2019-07-10 | — | — | EP | disclosed |