Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637121 | 0.83 | FTO (0.65) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL2019142 | 0.82 | FTO (0.63) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL20073857 | 0.80 | FTO (0.67) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL27833470 | 0.77 | FTO (0.83) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL220211 | 0.76 | FTO (1.00) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29413057 | 0.76 | FTO (1.00) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL15059064 | 0.76 | FTO (0.70) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL29995323 | 0.76 | FTO (0.70) | FTOMAPTMEN1HTTKMT2A | |
| Fluorescein SCHEMBL3892589 | 0.76 | FTO (0.85) | FTOMAPTMEN1HTTKMT2A | |
| SCHEMBL17035192 | 0.75 | FTO (0.60) | FTOMAPTMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135010-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-11 | — | — | WO | disclosed |
| EP-3508492-A1 | TIACUMICIN DERIVATIVES AND THEIR USE AS ANTIBIOTICS | Universität Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |