Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165110 | 0.87 | PDK2 (0.40) | PDK2PARP1EP300GAAHPGD | |
| SCHEMBL30125362 | 0.87 | PDK2 (0.40) | PDK2PARP1EP300GAAHPGD | |
| SCHEMBL10292862 | 0.87 | PDK2 (0.40) | PDK2PARP1GAAHPGDKMT2A | |
| SCHEMBL9898233 | 0.84 | MEN1 (0.45) | PDK2PARP1GAAHPGDKMT2A | |
| SCHEMBL1960034 | 0.83 | PDK2 (0.61) | PDK2 | |
| SCHEMBL1531822 | 0.83 | KMT2A (0.41) | PDK2PARP1EP300GAAHPGD | |
| SCHEMBL2200232 | 0.82 | PDK2 (0.41) | PDK2PARP1EP300GAAHPGD | |
| SCHEMBL30104202 | 0.82 | PDK2 (0.41) | PDK2PARP1EP300GAAHPGD | |
| SCHEMBL25954206 | 0.82 | PDK2 (0.38) | PDK2PARP1EP300KMT2AMEN1 | |
| SCHEMBL12424633 | 0.82 | ESR1 (0.40) | PDK2PARP1EP300GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943267-A | Method for synthesizing naphthopyran photochromic dye by using microchannel reactor | 广州盛色科技有限公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-111171619-B | Photochromic coating and preparation method thereof | 南京米兰达视光科学研究院有限公司 | 2021-11-30 | — | — | CN | disclosed |
| EP-3508554-B1 | PHOTOCHROMIC OPTICAL MATERIAL AND PREPARATION METHOD THEREFOR | JIANGSU SHIKEXINCAI COMPANY LTD (CN) | 2021-01-20 | — | — | EP | disclosed |
| CN-107778510-B | Spiropyran photochromic optical material and preparation method thereof | 南京米兰达视光科学研究院有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-107779072-B | Photochromic coating liquid and application thereof | 江苏视科新材料股份有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111171619-A | Photochromic coating and preparation method thereof | 南京米兰达视光科学研究院有限公司 | 2020-05-19 | — | — | CN | disclosed |
| CN-107722028-B | Photochromic optical material | 江苏视科新材料股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-107903889-B | Photochromic nano composite microsphere and application thereof | 江苏视科新材料股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-107722027-B | Preparation method of spiropyran photochromic nano composite microspheres | 江苏视科新材料股份有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-107828268-B | Spiropyran photochromic coating and preparation method thereof | 南京米兰达视光科学研究院有限公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-3508554-A1 | PHOTOCHROMIC OPTICAL MATERIAL AND PREPARATION METHOD THEREFOR | Jiangsu Shikexincai Company Limited (CN) | 2019-07-10 | — | — | EP | disclosed |
| CN-104817528-A | Spiropyran photochromic compound and preparation method thereof | JIANGSU SHIKE PHOTOELECTRIC NEW MATERIALS CO LTD | 2015-08-05 | — | — | CN | disclosed |