Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113764 | 0.86 | GRIN1 (0.52) | PDE4BGRIN1GRIN2BKDM4ENPSR1 | |
| SCHEMBL21113912 | 0.85 | EPHX2 (0.46) | PDE4BNPSR1ALDH1A1HSD17B10RAB9A | |
| SCHEMBL22753865 | 0.84 | PDE4B (0.50) | PDE4BGRIN1GRIN2BKDM4ENPSR1 | |
| SCHEMBL21112114 | 0.84 | PDE4B (0.49) | PDE4BGRIN1GRIN2BKDM4ENPSR1 | |
| SCHEMBL21115318 | 0.84 | PDE4B (0.50) | PDE4BGRIN1GRIN2BKDM4ENPSR1 | |
| SCHEMBL21113756 | 0.83 | PDE4B (0.51) | PDE4BGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL21113905 | 0.83 | GRIN1 (0.49) | PDE4BGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL21113745 | 0.83 | USP2 (0.56) | GRIN1GRIN2BKDM4ENPSR1ALDH1A1 | |
| SCHEMBL21114090 | 0.82 | HSD17B10 (0.48) | PDE4BGRIN1GRIN2BKDM4ENPSR1 | |
| SCHEMBL21114204 | 0.82 | SMN1; SMN2 (0.52) | KDM4ENPSR1ALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502099-B1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3502099-A1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | Medshine Discovery Inc. (CN) | 2019-06-26 | — | — | EP | disclosed |