Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21113764 | 0.85 | GRIN1 (0.52) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22753865 | 0.85 | PDE4B (0.50) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21112114 | 0.85 | PDE4B (0.49) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21115329 | 0.85 | GRIN1 (0.53) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21115333 | 0.84 | PDE4B (0.49) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21114090 | 0.84 | HSD17B10 (0.48) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21113032 | 0.83 | PDE4B (0.51) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21115452 | 0.83 | KMT2A (0.54) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL21113771 | 0.82 | USP2 (0.50) | USP2GLAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21112855 | 0.82 | USP2 (0.50) | USP2GLAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502099-B1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3502099-A1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | Medshine Discovery Inc. (CN) | 2019-06-26 | — | — | EP | disclosed |