Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171949 | 0.83 | TAAR1 (0.66) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL30798825 | 0.83 | TAAR1 (0.66) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL28797876 | 0.80 | TAAR1 (0.56) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL30093277 | 0.80 | TAAR1 (0.56) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL15314804 | 0.79 | TAAR1 (0.47) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL12124994 | 0.78 | TAAR1 (0.55) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL13859022 | 0.78 | TAAR1 (0.50) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL24758551 | 0.78 | TAAR1 (0.48) | TAAR1SLC6A3IDO1ALDH1A1SLC6A2 | |
| SCHEMBL10294046 | 0.77 | RIPK1 (0.55) | TAAR1RIPK1MEN1KMT2AOPRM1 | |
| SCHEMBL12089006 | 0.77 | TAAR1 (0.53) | TAAR1RIPK1MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502099-B1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | MEDSHINE DISCOVERY INC (CN) | 2020-12-09 | — | — | EP | disclosed |
| EP-3502099-A1 | CYCLIC COMPOUND ACTING AS PDE4 INHIBITOR | Medshine Discovery Inc. (CN) | 2019-06-26 | — | — | EP | disclosed |