Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13765688 | 0.80 | KDM4E (0.44) | KDM4EPIK3CDNAAA | |
| SCHEMBL13330255 | 0.78 | KDM4E (0.46) | KDM4EPIK3CDNAAA | |
| SCHEMBL2049359 | 0.77 | — | — | |
| SCHEMBL1031977 | 0.77 | KDM4E (0.41) | KDM4EPIK3CDNAAA | |
| SCHEMBL21278406 | 0.76 | KDM4E (0.36) | KDM4EPIK3CD | |
| SCHEMBL10413751 | 0.74 | KDM4E (0.40) | KDM4EPIK3CDNAAA | |
| SCHEMBL8865956 | 0.74 | KDM4E (0.40) | KDM4EPIK3CDNAAA | |
| SCHEMBL13256003 | 0.73 | KDM4E (0.41) | KDM4EPIK3CDNAAA | |
| SCHEMBL1106523 | 0.73 | — | — | |
| SCHEMBL22017454 | 0.72 | KDM4E (0.44) | KDM4EPIK3CDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10611739-B2 | Process for preparation of lactone derivatives and intermediates thereof | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2020-04-07 | — | — | US | disclosed |
| US-20190210981-A1 | PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
| CN-109843860-A | Process for producing lactone derivative and intermediate thereof | 上海泓博智源医药股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611739-B2 | Process for preparation of lactone derivatives and intermediates thereof | LSS, CYP3A4, HCCS | KDM4E 3001/4885PIK3CD 542/4885NAAA 2781/4885 |
| US-20190210981-A1 | PROCESS FOR PREPARATION OF LACTONE DERIVATIVES AND INTERMEDIATES THEREOF | LSS, CYP3A4, HCCS | KDM4E 3001/4885PIK3CD 542/4885NAAA 2781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.