Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22067189 | 0.89 | PIK3CD (0.49) | KDM4EPIK3CDNAAAGAA | |
| SCHEMBL13330255 | 0.85 | KDM4E (0.46) | KDM4EPIK3CDNAAA | |
| SCHEMBL13256003 | 0.83 | KDM4E (0.41) | KDM4EPIK3CDNAAA | |
| SCHEMBL19091731 | 0.80 | PIK3CD (0.46) | KDM4EPIK3CDNAAA | |
| SCHEMBL22065917 | 0.78 | PIK3CD (0.45) | KDM4EPIK3CDNAAA | |
| SCHEMBL8865732 | 0.77 | KDM4E (0.38) | KDM4EPIK3CDNAAA | |
| SCHEMBL19091490 | 0.77 | PIK3CD (0.44) | KDM4EPIK3CDNAAA | |
| SCHEMBL22065914 | 0.77 | PIK3CD (0.44) | KDM4EPIK3CDNAAA | |
| SCHEMBL1106523 | 0.76 | — | — | |
| SCHEMBL9069291 | 0.75 | NAAA (0.48) | KDM4EPIK3CDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157096-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157096-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | KDM4E 3882/4885PIK3CD 2677/4885NAAA 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.