SCHEMBL21113982

SCHEMBL21113982

O=C(O)c1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.70
LMNA P02545 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
ALOX12 P18054 1/20 0.66
ADRA1A P35348 1/20 0.66
TK2 O00142 1/20 0.65
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
TSHR P16473 1/20 0.64
BLM P54132 1/20 0.64
PMP22 Q01453 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21158662 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL5981723 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL21114095 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL5981728 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL22607139 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL21158663 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL22641566 1.00 TK1 (0.70) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL9780661 0.89 TK1 (0.69) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL5983020 0.89 TK1 (0.69) TK1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL15285228 0.89 TK1 (0.69) TK1LMNASMN1; SMN2ALOX12ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
EP-3736568-B1 DETECTION METHOD FOR ANALOG DERIVED FROM TRIFLURIDINE TAIHO PHARMACEUTICAL CO LTD (JP) 2024-09-18 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
CN-116286830-A Aptamer 中国人民解放军军事科学院军事医学研究院 2023-06-23 CN claimed
CN-115151263-A Aptamers and uses thereof 爱普济德生物技术有限公司 2022-10-04 CN claimed
EP-3736568-A1 DETECTION METHOD FOR ANALOG DERIVED FROM TRIFLURIDINE Taiho Pharmaceutical Co., Ltd. (JP) 2020-11-11 EP claimed
US-10816517-B2 Method for detecting trifluridine-related substance by high-performance liquid chromatography TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-10-27 US claimed
US-20190212309-A1 METHOD FOR DETECTING TRIFLURIDINE-RELATED SUBSTANCE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TAIHO PHARMACEUTICAL CO., LTD. (JP) 2019-07-11 US claimed
EP-4665405-A1 DNA COMPOSITIONS COMPRISING MODIFIED URACIL Flagship Pioneering Innovations VII, LLC (US) 2025-12-24 EP disclosed
EP-4580609-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2025-07-09 EP disclosed
CN-113785062-B Aptamer and use thereof 爱普济德生物技术有限公司 2025-05-16 CN disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 CN disclosed
WO-2025049632-A1 COMPOSITIONS AND METHODS FOR BROAD DELIVERY OF RNA TO TISSUE REJUVENATION TECHNOLOGIES INC. (US) 2025-03-06 WO disclosed
CN-119552875-A Aptamer and use thereof 爱普济德生物技术有限公司 2025-03-04 CN disclosed
EP-3519571-B1 COMPOSITIONS, METHODS AND SYSTEMS FOR IDENTIFYING CANDIDATE NUCLEIC ACID AGENT APTITUDE MEDICAL SYSTEMS INC (US) 2022-07-27 EP disclosed
CN-107236011-B Nucleoside compound or salt thereof, nucleic acid and application thereof 中国人民解放军军事医学科学院毒物药物研究所 2020-11-27 CN disclosed
EP-3736568-A1 DETECTION METHOD FOR ANALOG DERIVED FROM TRIFLURIDINE Taiho Pharmaceutical Co., Ltd. (JP) 2020-11-11 EP disclosed
US-10816517-B2 Method for detecting trifluridine-related substance by high-performance liquid chromatography TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-10-27 US disclosed
US-10809237-B2 Method for detecting trifluridine-related substance by high-performance liquid chromatography TAIHO PHARMACEUTICAL CO., LTD. (JP) 2020-10-20 US disclosed
US-20190212309-A1 METHOD FOR DETECTING TRIFLURIDINE-RELATED SUBSTANCE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TAIHO PHARMACEUTICAL CO., LTD. (JP) 2019-07-11 US disclosed