Dl-Dithiothreitol

Dl-Dithiothreitol

SCHEMBL21114401

OC(CS)C(O)CS.OC(CS)C(O)CS

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
NR1I2 O75469 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.30
ADAM17 P78536 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC7A11 Q9UPY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Dithiothreitol SCHEMBL6206522 1.00 LMNA (0.44) LMNANR1I2ALDH1A1CYP1A2HTT
Dl-Dithiothreitol SCHEMBL28874716 1.00 LMNA (0.44) LMNANR1I2ALDH1A1CYP1A2HTT
Dl-Dithiothreitol SCHEMBL78921 1.00
Dl-Dithiothreitol SCHEMBL14496668 1.00
Dl-Dithiothreitol SCHEMBL87345 1.00
Dl-Dithiothreitol SCHEMBL10601 1.00
Dl-Dithiothreitol SCHEMBL17370231 1.00
Dithiothreitol SCHEMBL538995 1.00
Dl-Dithiothreitol SCHEMBL21114400 1.00 LMNA (0.44) LMNANR1I2ALDH1A1CYP1A2HTT
Dl-Dithiothreitol SCHEMBL9773253 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105158477-A Quantum dot fluorescent probe and application thereof SHANGHAI INST MICROSYS & INF 2015-12-16 CN claimed
CN-116808234-A Modified TLR2 targeting peptide, targeting drug and application thereof 西安交通大学医学院第一附属医院 2023-09-29 CN disclosed
CN-116640843-A Biomarkers for sarcopenia associated with cirrhosis 重庆医科大学附属第二医院 2023-08-25 CN disclosed
EP-4214226-A1 METHODS OF PROCESSING A SAMPLE FOR PEPTIDE MAPPING ANALYSIS Amgen Inc. (US) 2023-07-26 EP disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-103613669-B Polypeptide for inhibiting cell proliferation and inducing apoptosis, preparation method and application thereof 华中科技大学同济医学院附属同济医院 2016-08-17 CN disclosed
CN-103613669-A Polypeptide for inhibiting cell proliferation and inducing apoptosis, preparation method and application thereof AFFILIATED TONGJI HOSPITAL OF TONGJI MEDICAL COLLEGE OF HUAZHONG UNIV SCI & TECH 2014-03-05 CN disclosed
CN-101556281-B Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH 2012-12-05 CN disclosed
CN-101556281-A Biological detection method of PPAR active pollutant UNIV HUAZHONG SCIENCE TECH (CN) 2009-10-14 CN disclosed
CN-101509035-A Lung cancer parting gene sequence and uses thereof CHINESE PLA GENERAL HOSPITAL (CN) 2009-08-19 CN disclosed
CN-100489097-C Method for preparing protein using endogenetic angiogenesis inhibitive factor Arresten gene ZHENG JINPING TANG HAIYING (CN) 2009-05-20 CN disclosed
CN-1884527-A Method for preparing protein using endogenetic angiogenesis inhibitive factor Arresten gene ZHENG JINPING (CN) 2006-12-27 CN disclosed