SCHEMBL21114537

SCHEMBL21114537

CCCCCC(CC)Oc1ccccc1C(=O)N=NC(C)C([SiH3])(N=NC(=O)c1ccccc1OC(CC)CCCCC)N=NC(=O)c1ccccc1OC(CC)CCCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 3/20 0.33
LMNA P02545 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
NR1I2 O75469 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRA2A P08913 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CA2 P00918 1/20 0.32
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114634 0.87 PRSS1 (0.39) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21114690 0.83 PRSS1 (0.36) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL20981401 0.82 PRSS1 (0.41) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21114681 0.81 IRAK4 (0.48) ALDH1A1LMNAKDM4EADRA2AIRAK4
SCHEMBL21114599 0.81 ALDH1A1 (0.46) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21114621 0.80 HCRTR1 (0.43) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL21114501 0.79 PRSS1 (0.41) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21114678 0.78 PRSS1 (0.39) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL21840883 0.78 PRSS1 (0.40) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL20981413 0.77 PRSS1 (0.39) PRSS1PRSS2PRSS3ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954361-B2 Curing agent for silicone rubber compounds NITROCHEMIE ASCHAU GMBH (DE) 2021-03-23 US claimed
EP-3484897-B1 HARDENER FOR SILICONE RUBBER MASSES NITROCHEMIE GMBH (DE) 2020-12-23 EP claimed
EP-3484970-B1 COMPOSITION FOR SILICONE RUBBER MASSES NITROCHEMIE GMBH (DE) 2020-07-08 EP claimed
US-20210324195-A1 Composition for Silicone Rubber Masses NITROCHEMIE ASCHAU GMBH (DE) 2021-10-21 US disclosed
US-10954361-B2 Curing agent for silicone rubber compounds NITROCHEMIE ASCHAU GMBH (DE) 2021-03-23 US disclosed
US-20190211187-A1 CURING AGENT FOR SILICONE RUBBER COMPOUNDS NITROCHEMIE ASCHAU GMBH (DE) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10954361-B2 Curing agent for silicone rubber compounds CARM1, PRMT1, SRRM2 PRSS1 3279/4885PRSS2 4201/4885PRSS3 4198/4885
US-20190211187-A1 CURING AGENT FOR SILICONE RUBBER COMPOUNDS CARM1, PRMT1, SRRM2 PRSS1 3279/4885PRSS2 4201/4885PRSS3 4198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.