SCHEMBL21114699

SCHEMBL21114699

COc1ccccc1C(=O)N=N[Si](N=NC(=O)c1ccccc1OC)(N=NC(=O)c1ccccc1OC)N=NC(=O)c1ccccc1OC

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.49
HPGD P15428 2/20 0.46
ALDH1A1 P00352 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
STAT3 P40763 1/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 2/20 0.45
ABCG2 Q9UNQ0 1/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CNR2 P34972 1/20 0.44
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114658 0.84 CTSD (0.47) CTSDHPGDALDH1A1RXFP1STAT3
SCHEMBL21114590 0.82 IRAK4 (0.57) ALDH1A1RXFP1KCNK3KCNK9
SCHEMBL21114671 0.82 HCRTR1 (0.53) HPGDALDH1A1RXFP1HTTMEN1
SCHEMBL20981427 0.81 CTSD (0.50) CTSDHPGDALDH1A1RXFP1STAT3
SCHEMBL3261986 0.78 HPGD (0.49) CTSDHPGDALDH1A1STAT3NPC1
SCHEMBL21114687 0.77 CTSD (0.46) CTSDHPGDALDH1A1STAT3NPC1
SCHEMBL21114675 0.76 CTSD (0.45) CTSDHPGDALDH1A1RXFP1STAT3
SCHEMBL30582803 0.75 CTSD (0.51) CTSDHPGDALDH1A1RXFP1STAT3
SCHEMBL20981408 0.74 NPC1 (0.44) CTSDHPGDALDH1A1STAT3NPC1
SCHEMBL20981449 0.74 CTSD (0.47) CTSDHPGDALDH1A1STAT3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10954361-B2 Curing agent for silicone rubber compounds NITROCHEMIE ASCHAU GMBH (DE) 2021-03-23 US claimed
EP-3484897-B1 HARDENER FOR SILICONE RUBBER MASSES NITROCHEMIE GMBH (DE) 2020-12-23 EP claimed
EP-3484970-B1 COMPOSITION FOR SILICONE RUBBER MASSES NITROCHEMIE GMBH (DE) 2020-07-08 EP claimed
US-20210324195-A1 Composition for Silicone Rubber Masses NITROCHEMIE ASCHAU GMBH (DE) 2021-10-21 US disclosed
US-10954361-B2 Curing agent for silicone rubber compounds NITROCHEMIE ASCHAU GMBH (DE) 2021-03-23 US disclosed
US-20190211187-A1 CURING AGENT FOR SILICONE RUBBER COMPOUNDS NITROCHEMIE ASCHAU GMBH (DE) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10954361-B2 Curing agent for silicone rubber compounds CARM1, PRMT1, SRRM2 CTSD 4373/4885HPGD 3462/4885ALDH1A1 1173/4885
US-20190211187-A1 CURING AGENT FOR SILICONE RUBBER COMPOUNDS CARM1, PRMT1, SRRM2 CTSD 4373/4885HPGD 3462/4885ALDH1A1 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.