SCHEMBL21115026

SCHEMBL21115026

CC(C)C(O)CNC(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
CASP7 P55210 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
ADRB2 P07550 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24192879 0.85 LMNA (0.38) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL24192305 0.82 LMNA (0.39) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL25907484 0.82 LMNA (0.39) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL24192696 0.82 LMNA (0.39) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL24192872 0.82 LMNA (0.39) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL20228215 0.80
SCHEMBL20228210 0.78 LMNA (0.37) LMNACYP3A4CYP2C9TSHRCASP7
SCHEMBL756930 0.78
SCHEMBL437044 0.78
SCHEMBL438765 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10577439-B2 Polymers and DNA copolymer coatings ILLUMINA CAMBRIDGE LIMITED (GB) 2020-03-03 US disclosed
US-20190194363-A1 NOVEL POLYMERS AND DNA COPOLYMER COATINGS ILLUMINA CAMBRIDGE LIMITED (GB) 2019-06-27 US disclosed