Ilatreotide

Ilatreotide

SCHEMBL2111506

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccccc2)NC[C@@]2(O)OC[C@@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)CSSC[C@@H](C(=O)N[C@H](CO)[C@@H](C)O)NC1=O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SSTR2 P30874 18/20 0.91
SSTR5 P35346 10/20 0.91
SSTR3 P32745 8/20 0.91
SSTR4 P31391 8/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ilatreotide SCHEMBL29509152 1.00 SSTR2 (0.91) SSTR2SSTR5SSTR3SSTR4
SCHEMBL23901126 0.84 SSTR2 (0.88) SSTR2SSTR5SSTR3SSTR4
SCHEMBL23482744 0.84 SSTR2 (0.88) SSTR2SSTR5SSTR3SSTR4
SCHEMBL22388803 0.83 SSTR2 (0.87) SSTR2SSTR5SSTR3SSTR4
SCHEMBL25504914 0.83 SSTR2 (0.87) SSTR2SSTR5SSTR3SSTR4
SCHEMBL22389054 0.83 SSTR2 (0.87) SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL21944070 0.83 SSTR2 (1.00) SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL21840389 0.83 SSTR2 (1.00) SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL23424109 0.83 SSTR2 (1.00) SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL17404479 0.83 SSTR2 (1.00) SSTR2SSTR5SSTR3SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
US-12605447-B2 Stable formulations for radionuclide complexes ITM SOLUCIN GMBH (DE) 2026-04-21 US disclosed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
US-12491272-B2 Stable, concentrated radionuclide complex solutions ADVANCED ACCELERATOR APPLICATIONS SA (FR) 2025-12-09 US disclosed
US-20250345468-A1 COMBINATION TREATMENT OF SMALL-CELL LUNG CANCER ITM ISOTOPE TECH MUNICH SE (DE) 2025-11-13 US disclosed
US-20250332301-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION NOVARTIS AG (CH) 2025-10-30 US disclosed
EP-4640241-A2 STABLE, CONCENTRATED RADIONUCLIDE COMPLEX SOLUTIONS Advanced Accelerator Applications S.A. (FR) 2025-10-29 EP disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345468-A1 COMBINATION TREATMENT OF SMALL-CELL LUNG CANCER SSTR1, SSTR3, SSTR2 SSTR2 3/4885SSTR5 4/4885SSTR3 2/4885
US-20250332301-A1 STABLE, CONCENTRATED RADIOPHARMACEUTICAL COMPOSITION RAB5IF, TMEM14C, PAICS SSTR2 418/4885SSTR5 164/4885SSTR3 241/4885
US-12605447-B2 Stable formulations for radionuclide complexes EPOR, CD47, PRCP SSTR2 15/4885SSTR5 14/4885SSTR3 19/4885
US-12491272-B2 Stable, concentrated radionuclide complex solutions EPOR, PAICS, XPO5 SSTR2 461/4885SSTR5 188/4885SSTR3 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.