Ilatreotide

SCHEMBL29509152

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](Cc2ccccc2)NC[C@@]2(O)OC[C@@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]2O)CSSC[C@@H](C(=O)N[C@H](CO)[C@@H](C)O)NC1=O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	SSTR2	P30874	18/20	0.91

▸	SSTR5	P35346	10/20	0.91

▸	SSTR3	P32745	8/20	0.91

▸	SSTR4	P31391	8/20	0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Ilatreotide SCHEMBL2111506	1.00	SSTR2 (0.91)	SSTR2SSTR5SSTR3SSTR4
SCHEMBL23901126	0.84	SSTR2 (0.88)	SSTR2SSTR5SSTR3SSTR4
SCHEMBL23482744	0.84	SSTR2 (0.88)	SSTR2SSTR5SSTR3SSTR4
SCHEMBL22388803	0.83	SSTR2 (0.87)	SSTR2SSTR5SSTR3SSTR4
SCHEMBL25504914	0.83	SSTR2 (0.87)	SSTR2SSTR5SSTR3SSTR4
SCHEMBL22389054	0.83	SSTR2 (0.87)	SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL21944070	0.83	SSTR2 (1.00)	SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL21840389	0.83	SSTR2 (1.00)	SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL23424109	0.83	SSTR2 (1.00)	SSTR2SSTR5SSTR3SSTR4
Octreotide SCHEMBL19232283	0.83	SSTR2 (1.00)	SSTR2SSTR5SSTR3SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3782649-B1	BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS	ASCENDIS PHARMA AS (DK)	2025-05-14	—	—	EP	disclosed
US-20220088150-A1	Octreotide Microsphere-Based Arterial Embolization for Treating Obesity	BIOVENA SCIENCE LLC (US)	2022-03-24	—	—	US	disclosed