SCHEMBL21115536

SCHEMBL21115536

C=C(C)C(=O)OCCCc1cc(-c2ccc(-c3ccc(C4CCCCC4)cc3)cc2C)cc(CCCOC(=O)C(=C)C)c1OCCC(CC)(CO)CO

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 5/20 0.33
S1PR5 Q9H228 4/20 0.33
S1PR3 Q99500 3/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115555 0.93 CNR1 (0.30)
SCHEMBL21115704 0.93 S1PR1 (0.32) S1PR1S1PR5S1PR3FFAR4CYP3A4
SCHEMBL21115608 0.91 MMP2 (0.32)
SCHEMBL21097861 0.91 FFAR4 (0.36) FFAR4CYP3A4CYP2C9
SCHEMBL21115603 0.90 FFAR4 (0.30) FFAR4
SCHEMBL21096354 0.89 FFAR4 (0.34) FFAR4CYP3A4CYP2C9
SCHEMBL21115566 0.89 CNR1 (0.33) FFAR4
SCHEMBL21115418 0.88 CNR1 (0.32)
SCHEMBL21043103 0.88 FFAR4 (0.34) FFAR4CYP3A4CYP2C9
SCHEMBL21115788 0.88 POLB (0.32) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3502209-B1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2020-10-14 EP disclosed
EP-3502209-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT Merck Patent GmbH (DE) 2019-06-26 EP disclosed