Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21097885 | 0.96 | CNR2 (0.35) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL17070505 | 0.93 | HTT (0.36) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL18646502 | 0.93 | HTT (0.36) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL18646513 | 0.92 | HTT (0.37) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL21098594 | 0.90 | L3MBTL1 (0.35) | HTTMAPTMAPK1L3MBTL1MEN1 | |
| SCHEMBL17063576 | 0.89 | CNR2 (0.36) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL18645610 | 0.89 | CNR2 (0.36) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL18645623 | 0.88 | RARB (0.40) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL21984947 | 0.88 | PTPN11 (0.36) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL18645804 | 0.88 | CNR2 (0.36) | HTTMAPTMAPK1APAF1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-B1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |