Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | RARG | P13631 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21115590 | 0.95 | PPARD (0.36) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21115599 | 0.95 | PPARD (0.38) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21115786 | 0.95 | PPARD (0.35) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21115426 | 0.94 | PPARD (0.35) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21115597 | 0.94 | RARA (0.33) | PPARDL3MBTL1MAPK1RARARARB | |
| SCHEMBL21115706 | 0.91 | PPARD (0.38) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21097785 | 0.89 | MAPK1 (0.34) | PPARDL3MBTL1MAPK1RARARARB | |
| SCHEMBL20288602 | 0.89 | MAPK1 (0.34) | PPARDPPARAPPARGL3MBTL1MAPK1 | |
| SCHEMBL21115423 | 0.89 | PPARD (0.34) | PPARDPPARAPPARGRARARARB | |
| SCHEMBL21115424 | 0.88 | RARA (0.34) | PPARDL3MBTL1MAPK1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-B1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |