Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | RARB | P10826 | 9/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070469 | 0.99 | S1PR1 (0.36) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL22540593 | 0.99 | S1PR1 (0.36) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL18645733 | 0.98 | THRA (0.36) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL17070526 | 0.96 | POLB (0.31) | TSHRS1PR1S1PR3 | |
| SCHEMBL22540639 | 0.96 | THRA (0.34) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL21115965 | 0.95 | THRA (0.37) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL21115795 | 0.95 | THRA (0.37) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL17070422 | 0.95 | S1PR1 (0.37) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL17070473 | 0.94 | THRA (0.35) | THRATHRBTSHRS1PR1RARB | |
| SCHEMBL22540579 | 0.94 | THRA (0.35) | THRATHRBTSHRS1PR1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |