SCHEMBL21115818

SCHEMBL21115818

C=CC(=O)OCCCCNC(=O)OCC1(C)CC2CC(C1)C1CC(C)(COC(=O)NCCCCOC(=O)C(=C)C)CCC21

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115821 0.99 TSHR (0.32) TSHRALDH1A1CYP3A4
SCHEMBL21115863 0.97
SCHEMBL21115827 0.94 TSHR (0.34) TSHR
SCHEMBL21115866 0.94 TSHR (0.35) TSHRALDH1A1CYP3A4
SCHEMBL21115870 0.93 TSHR (0.36) TSHRALDH1A1CYP3A4
SCHEMBL21115852 0.93 TSHR (0.36) TSHR
SCHEMBL21116147 0.91 TSHR (0.32) TSHR
SCHEMBL21115847 0.91 MEN1 (0.33) TSHR
SCHEMBL21115862 0.91 TSHR (0.33) TSHRALDH1A1CYP3A4
SCHEMBL21115957 0.90 MEN1 (0.39) TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2741728-B1 DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2019-06-26 EP disclosed