Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 12/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21115866 | 0.96 | TSHR (0.35) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL21115870 | 0.95 | TSHR (0.36) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL21115862 | 0.93 | TSHR (0.33) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL21115869 | 0.91 | ALDH1A1 (0.33) | ALDH1A1TSHRACHECYP3A4 | |
| SCHEMBL21115818 | 0.90 | TSHR (0.30) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL21115825 | 0.90 | EPHX2 (0.34) | MEN1KMT2AL3MBTL1ALDH1A1TSHR | |
| SCHEMBL21115821 | 0.90 | TSHR (0.32) | ALDH1A1TSHRCYP3A4 | |
| SCHEMBL21115863 | 0.88 | — | — | |
| SCHEMBL21115827 | 0.83 | TSHR (0.34) | MEN1KMT2AL3MBTL1TSHRACHE | |
| SCHEMBL20959943 | 0.81 | CYP19A1 (0.33) | ALDH1A1TSHRHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2741728-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-06-26 | — | — | EP | disclosed |