Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21115796 | 0.96 | IDO1 (0.33) | IDO1TSHRRARBCYP2C9PPARD | |
| SCHEMBL21115667 | 0.94 | TSHR (0.33) | IDO1TSHRPOLBAPEX1HTT | |
| SCHEMBL21115788 | 0.94 | POLB (0.32) | IDO1CYP2C9POLBAPEX1HTT | |
| SCHEMBL21675387 | 0.92 | TSHR (0.37) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21115756 | 0.91 | IDO1 (0.32) | IDO1TSHRCYP2C9PPARD | |
| SCHEMBL21115764 | 0.91 | S1PR1 (0.33) | IDO1TSHRRARBPPARDPOLB | |
| SCHEMBL21115673 | 0.91 | TSHR (0.35) | IDO1TSHRPOLBAPEX1HTT | |
| SCHEMBL21115630 | 0.91 | TSHR (0.34) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21097804 | 0.89 | TSHR (0.33) | IDO1TSHRCYP2C9POLBAPEX1 | |
| SCHEMBL20288237 | 0.89 | TSHR (0.33) | IDO1TSHRCYP2C9POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-B1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |