Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21096714 | 0.97 | PPARD (0.33) | S1PR1S1PR3RARBPPARDIDO1 | |
| SCHEMBL21115667 | 0.93 | TSHR (0.33) | IDO1TSHRPOLBAPEX1HTT | |
| SCHEMBL21115966 | 0.91 | IDO1 (0.33) | RARBPPARDIDO1TSHRPOLB | |
| SCHEMBL21675387 | 0.91 | TSHR (0.37) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL21115754 | 0.91 | S1PR1 (0.32) | S1PR1S1PR3PPARDIDO1TSHR | |
| SCHEMBL21115673 | 0.90 | TSHR (0.35) | IDO1TSHRPOLBAPEX1HTT | |
| SCHEMBL21115630 | 0.90 | TSHR (0.34) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL18645796 | 0.90 | RARB (0.39) | S1PR1S1PR3RARBPPARDIDO1 | |
| SCHEMBL21115577 | 0.89 | CNR1 (0.33) | TSHRNR1H2NR1H3 | |
| SCHEMBL21232267 | 0.89 | S1PR1 (0.34) | S1PR1S1PR3RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502209-B1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3502209-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |