Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583697 | 0.88 | THRB (0.40) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL27105761 | 0.82 | THRB (0.37) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL25848186 | 0.82 | THRB (0.39) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL24595649 | 0.82 | THRB (0.39) | THRBKDM4EHPGDNPC1RAB9A | |
| SCHEMBL21065595 | 0.82 | MAOB (0.45) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL29745824 | 0.82 | MAOB (0.45) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL25848155 | 0.81 | THRB (0.39) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL21116041 | 0.81 | THRB (0.36) | THRBSTSKDM4EALDH1A1MAPT | |
| SCHEMBL23713496 | 0.81 | STS (0.37) | THRBSTSKDM4EHPGDNPC1 | |
| SCHEMBL22624941 | 0.81 | THRB (0.38) | THRBSTSKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |