Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21116146 | 0.93 | THRB (0.32) | THRB | |
| SCHEMBL21116145 | 0.90 | — | — | |
| SCHEMBL21115953 | 0.89 | MEN1 (0.34) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL21115847 | 0.83 | MEN1 (0.33) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL21115827 | 0.82 | TSHR (0.34) | MEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL21115852 | 0.81 | TSHR (0.36) | MEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL21116147 | 0.80 | TSHR (0.32) | MEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL21115991 | 0.79 | TSHR (0.34) | MEN1KMT2AL3MBTL1ACHE | |
| SCHEMBL21115851 | 0.78 | TSHR (0.33) | ACHE | |
| SCHEMBL21115863 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2741728-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-06-26 | — | — | EP | disclosed |