Mobenzoxamine

Mobenzoxamine

SCHEMBL2111666

COc1ccc(C(OCCN2CCN(CCCC(=O)c3ccc(F)cc3)CC2)c2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 6/20 0.70
SLC6A3 Q01959 6/20 0.70
ALDH1A1 P00352 2/20 0.58
POLB P06746 1/20 0.58
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
LMNA P02545 1/20 0.56
TP53 P04637 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
MAPT P10636 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
NFKB1 P19838 1/20 0.56
SLC6A2 P23975 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
THPO P40225 1/20 0.56
MTOR P42345 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11068578 0.89 SLC6A4 (0.85) SLC6A4SLC6A3ALDH1A1MEN1NPC1
Hydrochloric Acid SCHEMBL10638536 0.88 SLC6A4 (0.74) SLC6A4SLC6A3ALDH1A1MEN1LMNA
SCHEMBL7721328 0.83 SLC6A4 (1.00) SLC6A4SLC6A3SLC6A2
Hydrochloric Acid SCHEMBL11077830 0.82 SLC6A4 (0.98) SLC6A4SLC6A3ALDH1A1MEN1LMNA
SCHEMBL10638396 0.82 SLC6A4 (0.88) SLC6A4SLC6A3SIGMAR1
Hydrochloric Acid SCHEMBL10635558 0.81 SLC6A4 (0.86) SLC6A4SLC6A3LMNASIGMAR1
SCHEMBL10552245 0.81 SLC6A4 (0.78) SLC6A4SLC6A3ALDH1A1MEN1NPC1
SCHEMBL10550540 0.81 SLC6A4 (0.78) SLC6A4SLC6A3ALDH1A1MEN1NPC1
SCHEMBL11828414 0.79 TSHR (0.64) ALDH1A1POLBMEN1TSHRKMT2A
SCHEMBL11833152 0.79 TSHR (0.64) SLC6A4ALDH1A1POLBMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-0194336-A2 Oral mobenzoxamine preparation Taiyo Pharmaceutical Industry Co., Ltd. (JP) 1986-09-17 EP claimed
US-4608366-A CLATHRATES; ANTISPASMODIC AGENTS, ANTIEMETICS TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) 1986-08-26 US claimed
JP-62148423-A None JP disclosed
JP-61207380-A None JP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US disclosed
EP-0194336-A2 Oral mobenzoxamine preparation Taiyo Pharmaceutical Industry Co., Ltd. (JP) 1986-09-17 EP disclosed
EP-0194336-A2 Oral mobenzoxamine preparation Taiyo Pharmaceutical Industry Co., Ltd. (JP) 1986-09-17 EP disclosed
JP-S61207380-A ORAL PREPARATION OF MOBENZOXAMINE TAIYO YAKUHIN KOGYO KK 1986-09-13 JP disclosed
US-4608366-A CLATHRATES; ANTISPASMODIC AGENTS, ANTIEMETICS TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) 1986-08-26 US disclosed
US-4608366-A CLATHRATES; ANTISPASMODIC AGENTS, ANTIEMETICS TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) 1986-08-26 US disclosed
US-4608366-A CLATHRATES; ANTISPASMODIC AGENTS, ANTIEMETICS TAIYO PHARMACEUTICAL INDUSTRY CO., LTD. (JP) 1986-08-26 US disclosed