Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 7/20 | 0.65 |
| ▸ | PDE2A | O00408 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385659 | 0.85 | ADA (0.46) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL20681481 | 0.84 | HPRT1 (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22364035 | 0.84 | HPRT1 (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL18877201 | 0.84 | HPRT1 (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21127784 | 0.82 | HPRT1 (0.47) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL7812368 | 0.79 | HPRT1 (0.47) | ALDH1A1LMNA | |
| (+)-Ehna SCHEMBL1742728 | 0.79 | ADA (1.00) | ADAPDE2ACYP3A4PDE4APDE4B | |
| (+)-Ehna SCHEMBL1740490 | 0.79 | ADA (1.00) | ADAPDE2ACYP3A4PDE4APDE4B | |
| (+)-Ehna SCHEMBL14985129 | 0.79 | ADA (1.00) | ADAPDE2ACYP3A4PDE4APDE4B | |
| Ehna SCHEMBL1742893 | 0.79 | ADA (1.00) | ADAPDE2ACYP3A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-11191719-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2021-12-07 | — | — | US | disclosed |
| US-10463611-B2 | Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration | STI PHARMA, LLC (US) | 2019-11-05 | — | — | US | disclosed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-20140154313-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2014-06-05 | — | — | US | disclosed |
| EP-2717860-A1 | CONTROLLED ABSORPTION WATER-SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUND FORMULATION FOR ONCE-DAILY ADMINISTRATION | STI Pharma, LLC (US) | 2014-04-16 | — | — | EP | disclosed |
| US-8454582-B2 | Methods and devices for the treatment of ocular conditions | SURMODICS, INC. (US) | 2013-06-04 | — | — | US | disclosed |
| EP-0009155-B1 | 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITION CONTAINING THE 9-HYDROXYALKYL-PURINES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4340726-A | PURINE COMPOUNDS HAVING IMMUNOMODULATOR, ANTIVIRAL ANTITUMOR AND ENZYME INHIBITOR ALTIVITY | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0036077-A2 | Esters of hydroxylalkyl-purines, processes for preparing them and therapeutical composition containing these esters as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1981-09-23 | — | — | EP | disclosed |
| US-4221910-A | IMMUNOPOTENTIATORS, VIRICIDES, ANTILEUKEMIA AGENTS | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221909-A | P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221794-A | Method of imparting immunomodulating and antiviral activity | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0009155-A1 | 9-Hydroxyalkyl-purines, processes for preparing them and therapeutical composition containing the 9-hydroxyalkyl-purines as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0009154-A1 | Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |