Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040856 | 0.89 | THRB (0.48) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8200163 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27829873 | 0.84 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5872182 | 0.83 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25837767 | 0.83 | TSHR (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22840976 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28082652 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10150487 | 0.83 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14980 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL766524 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3008096-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-06-26 | — | — | EP | disclosed |