Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | PPM1B | O75688 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.48 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PPP5C | P53041 | 1/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028639 | 1.00 | TDP1 (0.48) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL10029224 | 1.00 | TDP1 (0.48) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL2512784 | 1.00 | TDP1 (0.48) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL351863 | 1.00 | TDP1 (0.48) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL5833458 | 1.00 | TDP1 (0.48) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL16199087 | 0.90 | TDP1 (0.44) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL3199039 | 0.90 | TDP1 (0.44) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL6519226 | 0.90 | SMN1; SMN2 (0.44) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL6127457 | 0.90 | TDP1 (0.44) | TDP1KDM4EGMNNPPM1BLMNA | |
| SCHEMBL18723992 | 0.90 | TDP1 (0.44) | TDP1KDM4EGMNNPPM1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647693-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED (HK) | 2020-05-12 | — | — | US | disclosed |
| US-20190194159-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647693-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | EIF2AK2, POLRMT, SNRPE | TDP1 2430/4885KDM4E 1222/4885GMNN 520/4885 |
| US-20190194159-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | EIF2AK2, POLRMT, SNRPE | TDP1 2430/4885KDM4E 1222/4885GMNN 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.