Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.54 |
| ▸ | BCHE | P06276 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 5/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21118718 | 0.91 | BCHE (0.46) | ACHEBCHELMNAHPGDRAD52 | |
| SCHEMBL21118715 | 0.80 | APP (0.47) | ACHEBCHEHPGDKMT2AAPP | |
| SCHEMBL14869398 | 0.72 | BCHE (0.65) | ACHEBCHELMNAHPGDRAD52 | |
| SCHEMBL16280669 | 0.71 | ACHE (1.00) | ACHEBCHELMNARAD52KDM4E | |
| SCHEMBL20164615 | 0.67 | BCHE (0.58) | ACHEBCHELMNAHPGDRAD52 | |
| SCHEMBL14869431 | 0.67 | GAA (0.73) | ACHEBCHENPSR1 | |
| SCHEMBL15584268 | 0.66 | ACHE (0.57) | ACHEBCHELMNAHPGDRAD52 | |
| Hydrochloric Acid SCHEMBL20164600 | 0.66 | CDK1 (0.57) | ACHEBCHELMNAHPGDRAD52 | |
| SCHEMBL21055807 | 0.66 | BCHE (0.72) | ACHEBCHELMNARAD52KDM4E | |
| SCHEMBL14869402 | 0.65 | NPSR1 (0.64) | ACHEBCHELMNAHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323007-B1 | N2N N4-disubstituted quinazoline-2,4-diamines and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323007-B1 | N2N N4-disubstituted quinazoline-2,4-diamines and uses thereof | NQO2, NQO1, NIT2 | ACHE 14/4885BCHE 224/4885LMNA 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.