SCHEMBL21119906

SCHEMBL21119906

c1cnc2c(c1)ccc1ccc(-c3c4ccccc4c(-c4ccc5c(ccc6c7ccccc7oc56)n4)c4ccccc34)nc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
KDM4E B2RXH2 5/20 0.38
MAPT P10636 4/20 0.38
TSHR P16473 3/20 0.38
CYP3A4 P08684 2/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 2/20 0.38
GMNN O75496 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MMP2 P08253 1/20 0.38
CYP2D6 P10635 1/20 0.38
MMP9 P14780 1/20 0.38
ALOX15 P16050 1/20 0.38
NFKB1 P19838 1/20 0.38
MMP8 P22894 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21119851 0.92 LMNA (0.42) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119675 0.91 LMNA (0.41) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119771 0.91 LMNA (0.41) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119867 0.88 ADORA2A (0.37) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119681 0.87 LMNA (0.39) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119982 0.87 LMNA (0.40) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119586 0.85 CYP1A1 (0.37) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119780 0.85 LMNA (0.36) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL21119918 0.83 PDE4D (0.37) LMNAKDM4EMAPTTSHRCYP3A4
SCHEMBL15394099 0.83 CCR1 (0.42) LMNAKDM4EMAPTTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522139-B2 Organic light emitting diode LG DISPLAY CO., LTD. (KR) 2022-12-06 US disclosed
US-20190207123-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2019-07-04 US disclosed