Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.59 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.59 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561794 | 0.86 | — | — | |
| SCHEMBL15561792 | 0.79 | — | — | |
| SCHEMBL21130237 | 0.75 | SCN8A (0.54) | SCN8ASCN10A | |
| SCHEMBL15561695 | 0.75 | SCN8A (0.63) | SCN8ASCN10A | |
| SCHEMBL15917994 | 0.75 | — | — | |
| SCHEMBL18083728 | 0.75 | KCNK3 (0.53) | RXFP1 | |
| SCHEMBL15931112 | 0.74 | — | — | |
| SCHEMBL15561733 | 0.74 | SCN8A (1.00) | SCN8ASCN10A | |
| SCHEMBL20644110 | 0.74 | SCN8A (0.65) | SCN8ASCN10ALRRK2RXFP1 | |
| SCHEMBL15561797 | 0.74 | SCN8A (0.64) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951155-B1 | AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2019-06-19 | — | — | EP | disclosed |