Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 8/20 | 0.54 |
| ▸ | SCN10A | Q9Y5Y9 | 8/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15561877 | 0.85 | P4HTM (0.55) | — | |
| SCHEMBL15931116 | 0.78 | SCN8A (0.55) | SCN8ASCN10A | |
| SCHEMBL15562019 | 0.76 | SCN8A (0.64) | SCN8ASCN10A | |
| SCHEMBL21130238 | 0.75 | SCN8A (0.59) | SCN8ASCN10A | |
| SCHEMBL15561753 | 0.74 | SCN8A (0.63) | SCN8ASCN10A | |
| SCHEMBL15561822 | 0.74 | — | — | |
| SCHEMBL5417842 | 0.74 | — | — | |
| SCHEMBL4766809 | 0.73 | DHODH (0.52) | SCN8ASCN10A | |
| SCHEMBL9566852 | 0.73 | P4HTM (0.55) | — | |
| SCHEMBL15561737 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951155-B1 | AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2019-06-19 | — | — | EP | disclosed |