Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25956652 | 0.89 | KDM4E (0.40) | KDM4EATML3MBTL1 | |
| SCHEMBL22415195 | 0.89 | KDM4E (0.40) | KDM4EATML3MBTL1 | |
| SCHEMBL21539969 | 0.84 | ALDH1A1 (0.36) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL21388324 | 0.79 | KDM4E (0.36) | KDM4EATML3MBTL1 | |
| SCHEMBL23544455 | 0.79 | ALDH1A1 (0.33) | KDM4EALDH1A1ATML3MBTL1 | |
| SCHEMBL18568854 | 0.79 | KDM4E (0.40) | KDM4EATML3MBTL1 | |
| SCHEMBL22185942 | 0.78 | KDM4E (0.34) | KDM4EATML3MBTL1 | |
| SCHEMBL19003184 | 0.78 | CHRNA7 (0.36) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL21845438 | 0.78 | ATM (0.35) | KDM4EALDH1A1ATML3MBTL1HTT | |
| SCHEMBL20707565 | 0.77 | KDM4E (0.40) | KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502106-A1 | TRIAZINE COMPOUNDS SUBSTITUTED WITH BULKY GROUPS | Novaled GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |