SCHEMBL21131809

SCHEMBL21131809

N#Cc1ccc(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)cc1-c1cc(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)ccc1C#N

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AR P10275 16/20 0.42
ALOX5AP P20292 2/20 0.38
FEN1 P39748 2/20 0.38
PGR P06401 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21131807 0.95 AR (0.44) ARALOX5APFEN1PGR
SCHEMBL20849062 0.95 AR (0.39) ARALOX5APFEN1PGR
SCHEMBL20848881 0.93 AR (0.39) ARALOX5APFEN1PGR
SCHEMBL22985189 0.92 ALOX5AP (0.39) ARALOX5APFEN1PGR
SCHEMBL23253383 0.91 AR (0.41) ARALOX5APFEN1PGR
SCHEMBL21131808 0.91 AR (0.42) ARALOX5APFEN1PGR
SCHEMBL22985039 0.90 AR (0.35) ARALOX5APFEN1PGR
SCHEMBL20849175 0.90 AR (0.35) ARALOX5APFEN1PGR
SCHEMBL20848849 0.90 AR (0.40) ARALOX5APFEN1PGR
SCHEMBL20848585 0.90 AR (0.35) ARALOX5APFEN1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11380849-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2022-07-05 US disclosed
US-20190198778-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11380849-B2 Organic molecules for use in optoelectronic devices OR10J3, NOX3, ORC3 AR 912/4885ALOX5AP 4512/4885FEN1 2626/4885
US-20190198778-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES ORC3, OR10J3, NOX3 AR 1037/4885ALOX5AP 4380/4885FEN1 3011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.