SCHEMBL21131910

SCHEMBL21131910

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4ccc(-c5ccc(-c6cccc7ncccc67)cc5)c5ccccc45)cc3)n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
ACVR1 Q04771 3/20 0.49
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
ERN1 O75460 2/20 0.45
ATR Q13535 1/20 0.44
MCL1 Q07820 1/20 0.44
PIK3CA P42336 1/20 0.43
TOP1 P11387 1/20 0.43
CYP3A4 P08684 1/20 0.42
P2RX7 Q99572 1/20 0.42
CYP1A2 P05177 1/20 0.42
PDE5A O76074 1/20 0.42
TNF P01375 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
TGFBR1 P36897 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21131947 0.98 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL17944843 0.98 CA12 (0.55) CA12CA1CA2CA9ACVR1
SCHEMBL21131883 0.97 CA12 (0.51) CA12CA1CA2CA9ACVR1
SCHEMBL17932578 0.91 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL17720955 0.91 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL21159949 0.91 CA12 (0.49) CA12CA1CA2CA9ACVR1
SCHEMBL21131511 0.91 ACVR1 (0.50) CA12CA1CA2CA9ACVR1
SCHEMBL17932582 0.91 CA12 (0.50) CA12CA1CA2CA9ACVR1
SCHEMBL21131938 0.90 PIK3CA (0.53) CA12CA1CA2CA9ACVR1
SCHEMBL17944668 0.90 TOP1 (0.54) CA12CA1CA2CA9ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211563-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-20190198766-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-06-27 US disclosed