SCHEMBL21159949

SCHEMBL21159949

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cc5ccccc5cc4-c4ccc(-c5cccc6ncccc56)cc4)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
ACVR1 Q04771 4/20 0.48
ERN1 O75460 2/20 0.44
MCL1 Q07820 1/20 0.43
PIK3CA P42336 1/20 0.43
TOP1 P11387 1/20 0.42
ACACA Q13085 1/20 0.42
CYP3A4 P08684 1/20 0.41
ATR Q13535 1/20 0.41
CYP1A2 P05177 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
TNF P01375 1/20 0.41
MMP1 P03956 1/20 0.41
MMP9 P14780 1/20 0.41
DHODH Q02127 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17944843 0.93 CA12 (0.55) CA12CA1CA2CA9ACVR1
SCHEMBL21159915 0.92 PIK3CA (0.51) ACVR1PIK3CAACACACYP1A2MEN1
SCHEMBL21131910 0.91 CA12 (0.54) CA12CA1CA2CA9ACVR1
SCHEMBL21131947 0.90 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL17932578 0.89 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL17720955 0.89 CA12 (0.52) CA12CA1CA2CA9ACVR1
SCHEMBL17945868 0.89 ERN1 (0.50) CA12CA1CA2CA9ACVR1
SCHEMBL21131883 0.89 CA12 (0.51) CA12CA1CA2CA9ACVR1
SCHEMBL21131522 0.89 CA12 (0.43) CA12CA1CA2CA9ACVR1
SCHEMBL17945459 0.88 ACVR1 (0.48) CA12CA1CA2CA9ACVR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3498804-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-06-03 EP disclosed
EP-3498804-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2019-06-19 EP disclosed