SCHEMBL21132254

SCHEMBL21132254

CC1(C)CC(OC(=O)CCN(CCC(=O)OC2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
ALOX15 P16050 1/20 0.32
NPC1L1 Q9UHC9 2/20 0.31
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949180 0.98 GAA (0.41) GAAALOX15NPC1L1
SCHEMBL8949259 0.94 GAA (0.39) GAANAAA
SCHEMBL8374040 0.89 GAA (0.39) GAANPC1L1NAAA
SCHEMBL8531201 0.89 GAA (0.35) GAA
SCHEMBL9617630 0.86 GAA (0.45) GAANPC1L1NAAA
SCHEMBL8949112 0.85 GAA (0.34) GAA
SCHEMBL8949295 0.85 GAA (0.32) GAA
SCHEMBL10349500 0.84 GAA (0.44) GAANPC1L1NAAA
SCHEMBL8534147 0.84 NAAA (0.47) GAANPC1L1NAAA
SCHEMBL39117 0.84 GAA (0.51) GAANPC1L1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10618223-B2 Sacrificial high heat support materials for additive manufacturing processes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-14 US disclosed
US-20190193336-A1 SACRIFICIAL HIGH HEAT SUPPORT MATERIALS FOR ADDITIVE MANUFACTURING PROCESSES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-06-27 US disclosed