Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117642 | 0.86 | PIK3CD (0.44) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2117648 | 0.86 | PIK3CD (0.44) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2114960 | 0.85 | PIK3CD (0.43) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2114957 | 0.85 | PIK3CD (0.43) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2113490 | 0.85 | PIK3CD (0.47) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2113493 | 0.85 | PIK3CD (0.47) | PIK3CDKDM4EALDH1A1P2RX3 | |
| SCHEMBL2117053 | 0.79 | PIK3CD (0.40) | PIK3CDP2RX3 | |
| SCHEMBL2117048 | 0.79 | PIK3CD (0.40) | PIK3CDP2RX3 | |
| SCHEMBL2115956 | 0.78 | CNR2 (0.37) | PIK3CDP2RX3 | |
| SCHEMBL2115958 | 0.78 | CNR2 (0.37) | PIK3CDP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-04-19 | — | — | US | claimed |
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PDPK1, PIK3CA | PIK3CD 6/4885KDM4E 3834/4885ALDH1A1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.