Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114957 | 1.00 | PIK3CD (0.43) | PIK3CDALDH1A1KDM4EP2RX3CYP1A2 | |
| SCHEMBL2117642 | 0.87 | PIK3CD (0.44) | PIK3CDALDH1A1KDM4EP2RX3CYP1A2 | |
| SCHEMBL2117648 | 0.87 | PIK3CD (0.44) | PIK3CDALDH1A1KDM4EP2RX3CYP1A2 | |
| SCHEMBL2113493 | 0.86 | PIK3CD (0.47) | PIK3CDALDH1A1KDM4EP2RX3CYP1A2 | |
| SCHEMBL2113490 | 0.86 | PIK3CD (0.47) | PIK3CDALDH1A1KDM4EP2RX3CYP1A2 | |
| SCHEMBL2113258 | 0.85 | PIK3CD (0.45) | PIK3CDALDH1A1KDM4EP2RX3 | |
| SCHEMBL2117053 | 0.80 | PIK3CD (0.40) | PIK3CDP2RX3CYP1A2CYP2C9KRAS | |
| SCHEMBL2117048 | 0.80 | PIK3CD (0.40) | PIK3CDP2RX3CYP1A2CYP2C9KRAS | |
| SCHEMBL2115958 | 0.79 | CNR2 (0.37) | PIK3CDP2RX3CYP1A2CYP2C9KRAS | |
| SCHEMBL2115956 | 0.79 | CNR2 (0.37) | PIK3CDP2RX3CYP1A2CYP2C9KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095005-A1 | Fused Bicyclic Pyrazole Derivatives As Kinase Inhibitors | PI4KA, PDPK1, PIK3CA | PIK3CD 6/4885ALDH1A1 1059/4885KDM4E 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.