SCHEMBL21132779

Nc1ncnc2c1ncn2[C@H]1C[C@@H]2OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]cnc54)[C@H](OP(=O)(O)OC[C@H]2O1)[C@H]3F

nearest known ligand 0.89

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	STING1	Q86WV6	20/20	0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17858723	0.94	STING1 (1.00)	STING1
SCHEMBL17860566	0.94	STING1 (1.00)	STING1
SCHEMBL21417485	0.92	STING1 (1.00)	STING1
SCHEMBL29881490	0.92	STING1 (1.00)	STING1
SCHEMBL20341108	0.92	STING1 (1.00)	STING1
SCHEMBL18511077	0.92	STING1 (1.00)	STING1
SCHEMBL23476874	0.91	STING1 (1.00)	STING1
SCHEMBL17858636	0.91	STING1 (1.00)	STING1
SCHEMBL21133150	0.91	STING1 (1.00)	STING1
SCHEMBL30849574	0.91	STING1 (1.00)	STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3505527-A1	CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION	Invivogen (FR)	2019-07-03	—	—	EP	disclosed