SCHEMBL17860566

SCHEMBL17860566

Nc1ncnc2c1ncn2C1OC2COP(=O)(O)O[C@H]3CC(n4cnc5c(=O)[nH]cnc54)OC3COP(=O)(O)O[C@H]2[C@H]1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17858723 1.00 STING1 (1.00) STING1
SCHEMBL23476940 0.95 STING1 (0.90) STING1
SCHEMBL18310615 0.95 STING1 (0.90) STING1
SCHEMBL24038200 0.95 STING1 (0.90) STING1
SCHEMBL21132779 0.94 STING1 (0.89) STING1
SCHEMBL21343493 0.94 STING1 (1.00) STING1
SCHEMBL22887325 0.94 STING1 (1.00) STING1
SCHEMBL17858719 0.94 STING1 (1.00) STING1
SCHEMBL26201624 0.93 STING1 (0.87) STING1
SCHEMBL26013038 0.93 STING1 (0.86) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016096174-A1 FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION INVIVOGEN (FR) 2016-06-23 — — WO disclosed
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