SCHEMBL21133964

SCHEMBL21133964

CCCCCCC(C)(CCCC)c1cnc(OC)cn1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 6/20 0.33
▸ AR P10275 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ PABPC1 P11940 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ SIRT6 Q8N6T7 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ ACAT1 P24752 1/20 0.32
▸ SOAT1 P35610 1/20 0.32
▸ CNR1 P21554 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20793005 0.98 CNR2 (0.33) CNR2ARMEN1PABPC1KMT2A
SCHEMBL24656620 0.98 CNR2 (0.33) CNR2ARMEN1PABPC1KMT2A
SCHEMBL24656031 0.98 CNR2 (0.33) CNR2ARMEN1PABPC1KMT2A
SCHEMBL21783853 0.95 CNR2 (0.32) CNR2MEN1PABPC1KMT2ASIRT6
SCHEMBL18516775 0.93 CNR2 (0.34) CNR2MEN1PABPC1KMT2ASIRT6
SCHEMBL18522956 0.86 CNR2 (0.39) CNR2MEN1PABPC1KMT2ASIRT6
SCHEMBL23502537 0.85 CNR2 (0.34) CNR2KDM4ETSHRCNR1
SCHEMBL23502540 0.85 CNR2 (0.34) CNR2KDM4ETSHRCNR1
SCHEMBL22858660 0.80 GABRP (0.35) CNR2MEN1KMT2AKDM4EMAPT
SCHEMBL19646395 0.80 GABRP (0.35) CNR2MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10344016-B2 Bromotriazole intermediates AMGEN INC. (US) 2019-07-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10344016-B2 Bromotriazole intermediates APH1A, BRDT, APH1B CNR2 655/4885AR 474/4885MEN1 4001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback