Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 9/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056062 | 0.83 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL21056061 | 0.83 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL21056101 | 0.83 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL21056078 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL21134531 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL21056077 | 0.81 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL22640333 | 0.71 | MEN1 (0.37) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL7127279 | 0.71 | MAP2K1 (0.41) | GABRA1GABRG2GABRB3GABRB2MEN1 | |
| SCHEMBL16992749 | 0.70 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRB2GABRB1 | |
| SCHEMBL16992748 | 0.70 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRB2GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498273-A1 | PHARMACEUTICAL COMPOSITION FOR MODULATING THE RESPONSE OF A GABA-A RECEPTOR | Universität Wien (AT) | 2019-06-19 | — | — | EP | disclosed |