SCHEMBL21135043

SCHEMBL21135043

CCCCCC(C)(CCCC)n1cnc2cccnc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 4/20 0.37
▸ TLR7 Q9NYK1 3/20 0.37
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ TP53 P04637 1/20 0.36
▸ PABPC1 P11940 1/20 0.36
▸ PDE4A P27815 1/20 0.36
▸ PDE4B Q07343 1/20 0.36
▸ PDE4C Q08493 1/20 0.36
▸ PDE4D Q08499 1/20 0.36
▸ CNR1 P21554 1/20 0.35
▸ CNR2 P34972 1/20 0.35
▸ CSF1R P07333 1/20 0.35
▸ ASAH1 Q13510 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ PDE10A Q9Y233 1/20 0.34
▸ HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21115923 0.80 TP53 (0.39) TLR8MEN1KMT2ATP53PABPC1
SCHEMBL8931408 0.75 TP53 (0.41) MEN1KMT2ATP53PABPC1MAPT
SCHEMBL24360685 0.74 SLC9A1 (0.40) TLR8TLR7ASAH1PDE10A
SCHEMBL26083454 0.74 SLC9A1 (0.40) TLR8TLR7ASAH1PDE10A
SCHEMBL4860406 0.73 TP53 (0.36) MEN1KMT2ATP53PABPC1MAPT
SCHEMBL2193745 0.73 ASAH1 (0.39) MEN1KMT2ATP53PABPC1CNR1
SCHEMBL25504213 0.72 SLC9A1 (0.38) TLR8TLR7ASAH1PDE10A
SCHEMBL4867892 0.72 TP53 (0.43) MEN1KMT2ATP53PABPC1MAPT
SCHEMBL13749571 0.72 MEN1 (0.46) TLR8MEN1KMT2ATP53PABPC1
SCHEMBL13527216 0.71 MEN1 (0.45) TLR8MEN1KMT2ATP53PABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10818850-B2 Organic electroluminescence device and compound including nitrogen for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-27 — — US disclosed
US-20190198773-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOUND INCLUDING NITROGEN FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190198773-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOUND INCLUDING NITROGEN FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CHRM1, FOXM1 TLR8 2660/4885TLR7 1646/4885MEN1 112/4885
US-10818850-B2 Organic electroluminescence device and compound including nitrogen for organic electroluminescence device L1CAM, CHRM1, FOXM1 TLR8 2660/4885TLR7 1646/4885MEN1 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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