Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312329 | 0.86 | KDM4E (0.51) | MAPTKDM4ELMNAALDH1A1ATM | |
| SCHEMBL23272148 | 0.86 | KDM4E (0.51) | MAPTKDM4ELMNAALDH1A1ATM | |
| SCHEMBL21135206 | 0.84 | ATR (0.38) | ATRMAPTKDM4ELMNAGAA | |
| SCHEMBL21135207 | 0.84 | ATR (0.41) | ATRPIK3CDMAPTKDM4ELMNA | |
| SCHEMBL21135204 | 0.83 | PIK3CB (0.39) | ATRPIK3CDMAPTKDM4ELMNA | |
| SCHEMBL23272147 | 0.79 | KDM4E (0.55) | MAPTKDM4ELMNAALDH1A1ATM | |
| SCHEMBL30312330 | 0.79 | KDM4E (0.55) | MAPTKDM4ELMNAALDH1A1ATM | |
| SCHEMBL21135852 | 0.78 | PIK3CA (0.39) | PIK3CDPIK3CAMTORCDK4CCND3 | |
| SCHEMBL30312542 | 0.72 | ATR (0.49) | ATRMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL23272117 | 0.71 | KDM4E (0.57) | MAPTKDM4ELMNAALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |