Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135206 | 0.89 | ATR (0.38) | ATRPIK3CBALDH1A1MAPTKDM4E | |
| SCHEMBL21135204 | 0.87 | PIK3CB (0.39) | ATRPIK3CBALDH1A1MAPTKDM4E | |
| SCHEMBL23272155 | 0.85 | KDM4E (0.55) | ATRALDH1A1MAPTKDM4EATM | |
| SCHEMBL30312323 | 0.85 | KDM4E (0.55) | ATRALDH1A1MAPTKDM4EATM | |
| SCHEMBL21135208 | 0.84 | ATR (0.37) | ATRPIK3CBALDH1A1MAPTKDM4E | |
| SCHEMBL30312419 | 0.77 | MAPT (0.57) | ALDH1A1MAPTKDM4EATMLMNA | |
| SCHEMBL21054975 | 0.77 | MAPT (0.57) | ALDH1A1MAPTKDM4EATMLMNA | |
| SCHEMBL21135848 | 0.76 | PIK3CA (0.51) | PIK3CBALDH1A1MAPTKDM4ENPC1 | |
| SCHEMBL21135205 | 0.75 | ATR (0.53) | ATRNAPEPLDALDH1A1MAPTKDM4E | |
| SCHEMBL23272117 | 0.75 | KDM4E (0.57) | ALDH1A1MAPTKDM4EATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |