Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21054849 | 0.77 | PIKFYVE (0.60) | PIK3CDPIK3CAMTOR | |
| SCHEMBL30312424 | 0.77 | PIKFYVE (0.60) | PIK3CDPIK3CAMTOR | |
| SCHEMBL21135499 | 0.77 | FLT3 (0.41) | CNR2FLT3PIK3CDPIK3CAMTOR | |
| SCHEMBL21054122 | 0.73 | PIKFYVE (0.62) | FLT3PIK3CDPIK3CAMTOR | |
| SCHEMBL30312515 | 0.73 | PIKFYVE (0.62) | FLT3PIK3CDPIK3CAMTOR | |
| SCHEMBL21135863 | 0.73 | PIK3CD (0.51) | PIK3CDPIK3CG | |
| SCHEMBL21135486 | 0.69 | PIK3CD (0.41) | CNR2PIK3CDPIK3CAMTORMAPK14 | |
| SCHEMBL21135489 | 0.69 | PIK3CD (0.64) | CNR2PIK3CDSTAT3PIK3CG | |
| SCHEMBL30312417 | 0.69 | PIKFYVE (0.58) | PIK3CDPIK3CAMTOR | |
| SCHEMBL30312443 | 0.69 | PIKFYVE (0.58) | PIK3CDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |