Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135489 | 0.88 | PIK3CD (0.64) | PIK3CDPIK3R1PIK3CG | |
| SCHEMBL21135197 | 0.87 | PIK3CD (0.52) | PIK3CDPIK3R1PIK3CG | |
| SCHEMBL30312505 | 0.78 | PIKFYVE (0.62) | PIK3CDPARP1 | |
| SCHEMBL21053964 | 0.78 | PIKFYVE (0.62) | PIK3CDPARP1 | |
| SCHEMBL21135295 | 0.77 | STAT3 (0.50) | PIK3CDPIK3R1 | |
| SCHEMBL21135499 | 0.76 | FLT3 (0.41) | PIK3CDPIK3R1 | |
| SCHEMBL21135294 | 0.76 | MAPT (0.44) | PIK3CDPIK3CG | |
| SCHEMBL21135300 | 0.74 | PIKFYVE (0.44) | PIK3CDPIK3R1PBK | |
| SCHEMBL21135209 | 0.73 | CHEK1 (0.52) | PIK3CDPIK3CG | |
| SCHEMBL30312551 | 0.73 | PIKFYVE (0.59) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |